Name

Status

Main use

Chemical type

Physical state

Route

LD₅₀ (mg/kg)

Remarks

Acrolein

C

H

L

O

29

EHC 127; HSG 67

Alachlor

ISO

H

S

O

930

Adjusted classification; carcinogenic in rats and mice; DS 84

Aldicarb

ISO

I-S

C

S

O

0.93

DS 53; EHC 121; HSG 64

Arsenous oxide

C

R

S

O

180

Adjusted classification; minimum lethal dose 
for humans of 2 mg/kg; evidence of 
carcinogenicity for  humans is sufficient;
EHC 18; HSG 70

Brodifacoum

ISO

R

S

O

0.3

DS 57; EHC 175; HSG 93

Bromadialone

ISO

R

S

O

1.12

DS 88; EHC 175; HSG 94

Bromethalin

ISO

R

S

O

2

Calcium cyanide

C

FM

S

O

39

Adjusted classification; calcium cyanide is in Class IA as it 
reacts with moisture to produce hydrogen cyanide gas; 
the gas is not classified under the WHO system (see table 7)

Captafol

ISO

F

S

O

5,000

Adjusted classification; carcinogenic in rats and mice; 
HSG 49

Chlorfenvinphos

ISO

I

OP

L

O

10

Chlormephos

ISO

I

OP

L

O

7

Chlorophacinone

ISO

R

S

O

3.1

DS 62; EHC 175

Chlorthiophos

ISO

I

OP

L

O

9.1

Coumaphos

ISO

AC, MT

OP

L

O

7.1

CVP

N(J)

See chlorfenvinphos

Cycloheximide

ISO

F

S

O

2

DBCP

N(J)

See dibromochloropropane

Demephion-O and -S

ISO

I

OP

L

O

15

Demeton-O and -S

ISO

I

OP

L

O

2.5

DS 60

Dibromochloropropane

C

F-S

L

O

170

Adjusted classification; has been found to cause sterility in 
humans and is mutagenic and carcinogenic in animals

Difenacoum

ISO

R

S

O

1.8

EHC 175; HSG 95

Difethialone

ISO

R

S

O

0.56

EHC 175

Difolatan

N(J)

See captafol

Dimefox

ISO

I

OP

L

O

1

Volatile

Diphacinone

ISO

R

S

O

2.3

EHC 175

Disulfoton

ISO

I

OP

L

O

2.6

DS 68

EPN

N(A,J)

I

OP

S

O

14

Has been reported as causing delayed neurotoxicity in hens

Ethoprop

N(A)

See ethoprophos

Ethoprophos

ISO

I-S

OP

L

D

26

DS 70

Ethylthiometon

N(J)

See disulfoton

Fenamiphos

ISO

N

OP

L

O

15

DS 92

Fensulfothion

ISO

I

OP

L

O

3.5

DS 44

Flocoumafen

N(B)

R

S

O

0.25

EHC 175

Fonofos

ISO

I-S

OP

L

O

c8

Hexachlorobenzene

ISO

FST

S

D

10,000

Adjusted classification; has caused a serious outbreak of 
porphyria in humans; DS 26

Leptophos

ISO

I

OP

S

O

50

Adjusted classification; has been shown to cause delayed 
neurotoxicity; DS 38

M74

N(J)

See disulfoton

MBCP

N(J)

See leptophos

Mephosfolan

ISO

I

OP

L

O

9

Mercuric chloride

ISO

F-S

S

O

1

Merkaptophos

N(U)

When mixed with merkaptophosteolovy, 
see demeton -O and -S

Metaphos

N(U)

See parathion-methyl

Mevinphos

ISO

I

OP

L

D

4

DS 14

Nitrofen

ISO

H

S

O

c3,000

Adjusted classification; carcinogenic in rats and mice; 
teratogenic in several species tested; 
DS 84

Parathion

ISO

I

OP

L

O

13

DS 6; HSG 74

Parathion-methyl

ISO

I

OP

L

O

14

DS 7; EHC 145; HSG 75

Phenylmercury acetate

ISO

FST

S

O

24

Adjusted classification; highly toxic to mammals and very 
small doses have produced renal lesions; 
teratogenic in the rat

Phorate

ISO

I

OP

L

O

2

DS 75

Phosfolan

ISO

I

OP

L

O

9

Phosphamidon

ISO

I

OP

L

O

7

DS 74

Prothoate

ISO

AC,I

OP

L

O

8

Red squill

See scilliroside

Schradan

ISO

I

OP

L

O

9

Scilliroside

C

R

S

O

c0.5

Induces vomiting in mammals

Sodium fluoroacetate

C

R

S

O

0.2

DS 16

Sulfotep

ISO

I

OP

L

O

5

TEPP

ISO

AC

OP

L

O

1.1

Terbufos

ISO

I-S

OP

L

O

c2

Thiofos

N(U)

See parathion

Thionazin

ISO

N

OP

L

O

11

Timet

N(U)

See phorate

Name

Status

Main use

Chemical
type

Physical
state

Route

LD50 (mg/kg)

Remarks

Aldoxycarb

ISO

I,N

C

S

O

27

Aldrin

ISO

I

OC

S

D

98

DS41; EHC 91; HSG 21

Allyl alcohol

C

H

L

O

64

Highly irritant to skin and eyes

Aminocarb

ISO

I

C

S

O

50

Antu

ISO

R

S

O

8

Induces vomiting in dogs. Some impurities are 
carcinogenic

Azinphos-ethyl

ISO

I

OP

S

O

12

DS 72

Azinphos-methyl

ISO

I

OP

S

O

16

DS 59

Benfuracarb

N(B)

I

C

L

O

138

Bis(tributyltin) oxide

C

F,M

L

O

194

Irritant to skin. DS 65; EHC 15

Blasticidin-S

N(J)

F

S

O

16

Bromophos-ethyl

ISO

I

OP

L

O

71

Butocarboxim

ISO

I

C

L

O

158

Butoxycarboxim

ISO

I

C

L

D

288

Cadusafos

ISO

N,I

OP

L

O

37

Calcium arsenate

C

I

S

O

20

Carbofuran

ISO

I

C

S

O

8

DS 56

Carbophenothion

ISO

I

OP

L

O

32

3-chloro-1,2-propanediol

C

R

L

O

112

In non-lethal dosage is a sterilant for male rats

Coumachlor

ISO

R

S

D

33

Coumatetralyl

ISO

R

S

O

16

Crotoxyphos

ISO

I

OP

L

O

74

zeta-Cypermethrin

ISO

I

PY

L

O

c86

DDVF

N(U)

See dichlorvos

DDVP

N(J)

See dichlorvos

Delnav

N(U)

See dioxathion

Demeton-S-methyl

ISO

I

OP

L

O

40

DS 61

Demeton-S-methylsulphon

ISO

I

OP

S

O

37

Dichlorvos

ISO

I

OP

L

O

56

Volatile, DS 2; EHC 79; HSG 18

Dicrotophos

ISO

I

OP

L

O

22

Dieldrin

ISO

I

OC

S

O

37

DS 17: EHC 91

Dimetilan

N(A,B)

I

C

S

O

47

Dinoseb

ISO

H

CNP

L

O

58

Dinoseb acetate

ISO

H

CNP

L

O

60

Dinoterb

ISO

H

CNP

S

O

25

Dioxathion

ISO

I

OP

L

O

23

DMTP

N(J)

See methidathion

DNBP

N(J)

See dinoseb

DNBPA

N(J)

See dinoseb acetate

DNOC

ISO

I-S,H

CNP

S

O

25

EDDP

N(J)

See edifenfos

Edifenphos

ISO

F

OP

L

O

150

Endrin

ISO

I

OC

S

O

7

DS 1; EHC 130; HSG 60

ESP

N(J)

I

OP

L

O

105

Famphur

N(A)

I

OP

S

O

48

Flucythrinate

ISO

I

PY

L

O

c67

Irritant to skin and eyes

Fluoroacetamide

C

R

S

O

13

Formetanate

ISO

AC

C

S

O

21

Fosmethilan

ISO

I

OP

S

O

49

Irritant to skin and eyes.

Furathiocarb

N(B)

I-S

C

L

O

42

Heptenophos

ISO

I

OP

L

O

96

Isazofos

ISO

I-S

OP

L

O

60

Isofenphos

ISO

I

OP

oil

O

28

Isothioate

ISO

I

OP

L

O

150

Isoxathion

ISO

I

OP

L

O

112

Lead arsenate

C

L

S

O

c10

Mecarbam

ISO

I

C

oil

O

36

Mercuric oxide

ISO

O

S

O

18

Methamidophos

ISO

I

OP

L

O

30

HSG 79

Methidathion

ISO

I

OP

L

O

25

Methomyl

ISO

I

C

S

O

17

DS 55, EHC 178; HSG 97

Methyl-merkapto-phosteolovy

N(U)

See demeton-S-methyl

Metilmerkapto-phosoksid

N(U)

See oxydemeton-methyl

Metriltriazotion

N(U)

See azinphos-methyl

Monocrotophos

ISO

I

OP

S

O

14

HSG 80

MPP

N(J)

See fenthion

Nicotine

ISO

L

D

50

Omethoate

ISO

I

OP

L

O

50

Oxamyl

ISO

I

C

S

O

6

DS 54

Oxydemeton-methyl

ISO

I

OP

L

O

65

Oxydeprofos

N(B)

See ESP

Paris green

C

L

S

O

22

Copper-arsenic complex

Pentachlorophenol

ISO

I,F,H

CNP

S

D

80

Irritant to skin; EHC 71; HSG 19

Phenylmercury nitrate

C

FST

OM

S

Oral LD₅₀ not available, rat i.v. LD₅₀ is 27 mg/kg

Pirimiphos-ethyl

ISO

I

OP

L

O

140

Propaphos

N(J)

I

OP

L

O

70

Propetamphos

ISO

I

OP

L

O

106

Sodium arsenite

C

R

S

O

10

Sodium cyanide

C

R

S

O

6

Strychnine

C

R

S

O

16

TBTO

See bis-(tributyltin) oxide

Tefluthrin

N(B)

I-S

PY

S

O

c22

Thallium sulfate

C

R

S

O

11

DS 10

Thiofanox

ISO

I-S

C

S

O

8

Thiometon

ISO

I

OP

oil

O

120

DS 67

Thioxamyl

See oxyamyl

Triamiphos

ISO

F

S

O

20

Triazophos

ISO

I

OP

L

O

82

Triazotion

N(U)

See azinphos-ethyl

Vamidothion

ISO

I

OP

L

O

103

Warfarin

ISO

R

S

O

10

DS 35, EHC 175; HSG 96

Zinc phosphide

C

R

S

O

45

DS 24, EHC 73

Name

Status

Main Use

Chemical type

Physical state

Route

LD₅₀ (mg/kg)

Remarks

Alanycarb

ISO

I

C

S

O

330

Allidochlor

ISO

H

L

O

700

Irritant to skin and eyes

Anilofos

ISO

H

S

O

472

Azaconazole

N(B)

F

S

O

308

Azocyclotin

ISO

AC

OT

S

O

80

Bendiocarb

ISO

I

C

S

O

55

DS 52

Bensulide

ISO

H

L

O

270

Benzofos

N(U)

See phosalone

BHC

ISO

See HCH

gamma-BHC

See gamma-HCH

Bifenthrin

N(B)

I

PY

S

O

c55

Bilanafos

ISO

H

S

O

268

Binapacryl

ISO

AC

S

O

421

Bioallethrin

C

I

PY

L

O

c700

Bioallethrin, esbiothrin, esbiol and esdepalléthrine are 
members of the allethrin series; their toxicity varies 
considerably within this series according to 
concentrations of isomers.

Bisthiosemi

N(J)

R

S

O

c150

Induces vomiting in non-rodents

BPMC

See fenobucarb

Bromoxynil

ISO

H

S

O

190

Bronopol

N(B)

B

S

O

254

Bufencarb

ISO

I

C

S

O

87

Butamifos

ISO

H

L

O

630

Butenachlor

ISO

H

L

O

1,630

Butylamine

ISO

F

L

O

380

Irritant to skin

Camphechlor

ISO

I

OC

S

O

80

DS 20; EHC 45

Carbaryl

ISO

I

C

S

O

c300

DS 3; EHC 153; HSG 78

Carbosulfan

ISO

I

L

O

250

Cartap

ISO

I

S

O

325

Chloralose

C

R

S

O

400

Chlordane

ISO

I

OC

L

O

460

DS 36; EHC 34; HSG 13

Chlordimeform

ISO

AC

OC

S

O

340

Chlorphenamidine

N(J)

See chlordimeform

Chlorphonium

ISO

PGR

S

O

178

Irritant to skin and eyes

Chlorpyrifos

ISO

I

OP

S

O

135

DS 18

Clomazone

ISO

H

L

O

1,369

Copper sulfate

C

F

S

O

300

Cuprous oxide

C

F

S

O

470

Cyanazine

ISO

H

T

S

O

288

Cyanofenphos

ISO

I

OP

S

O

89

Has been reported as causing delayed neurotoxicity 
in hens; no longer manufactured

Cyanophos

ISO

I

OP

L

O

610

CYAP

N(J)

See cyanophos

Cyfluthrin

ISO

I

PY

S

O

c250

beta-Cyfluthrin

ISO

I

PY

S

O

450

Cyhalothrin

ISO

Ix

PY

oil

O

c144

EHC 99

lambda-Cyhalothrin

N(B)

I

PY

S

O

c56

EHC 142; HSG 38

CYP

N(J)

See cyanofenphos

Cypermethrin

ISO

I

PY

S

O

c250

DS 58; EHC 82; HSG 22

alpha-Cypermethrin

ISO

I

PY

S

O

c79

EHC 142

beta-Cypermethrin

ISO

I

PY

S

O

166

Cyphenothrin ((1R)-isomers)

ISO

I

PY

L

O

318

Cyprofuram

ISO

F

S

O

174

2,4-D

ISO

H

PA

S

O

375

DS 37; EHC 29; EHC 84

DAPA

N(J)

See fenaminosulf

DDT

ISO

I

OC

S

O

113

DS 21; EHC 9; EHC 83

Deltamethrin

ISO

I

PY

S

O

c135

DS 50; EHC 97; HSG 30

Dialifor

N(A,J)

See dialifos

Dialifos

ISO

I

OP

S

D

145

Di-allate

ISO

H

TC

L

O

395

Diazinon

ISO

I

OP

L

O

300

DS 45

Dibrom

N (Denmark)

See naled

Dichlofenthion

ISO

I-S

OP

L

O

270

Difenzoquat

ISO

H

S

O

470

Dimethoate

ISO

I

OP

S

O

c150

DS 42; EHC 90; HSG 20

Dinobuton

ISO

AC,F

S

O

140

Dioxabenzophos

N(B)

I

OP

S

O

125

Dioxacarb

ISO

I

C

S

O

90

Diquat

ISO

H

P

S

O

231

Irritant to skin, and eyes, and damages nails;
DS 40; EHC 39; HSG 52

Drazoxolon

(ISO)

FST

S

O

126

ECP

N(J)

See dichlofenthion

Endosulfan

ISO

I

OC

S

O

80

DS 15; EHC 40; HSG 17

Endothal-sodium

(ISO)

H

S

O

51

EPBP

N(J)

I-S

OP

oil

O

275

EPTC

ISO

H

TC

L

O

1,652

Esbiol

See bioallethrin

Esbiothrin

See bioallethrin

Esdepalléthrine

See bioallethrin

Esfenvalerate

ISO

I

PY

S

O

87

Ethiofencarb

ISO

I

C

L

O

411

Ethion

ISO

I

OP

L

O

208

Etrimfos

ISO

I

OP

L

O

1,800

Fenaminosulf

ISO

F-S

S

O

60

Fenazaquin

ISO

AC

S

O

134

Fenchlorphos

ISO

I

OP

L

O

1,740

DS 69

Fenitrothion

ISO

I

OP

L

O

503

DS 30; EHC 133; HSG 65

Fenobucarb

N(B)

I

C

S

O

620

Fenpropathrin

ISO

I

PY

S

O

c66

Fenthion

ISO

I,L

OP

L

D

586

DS 23

Fentin acetate

(ISO)

F

OT

S

O

125

DS 22

Fentin hydroxide

(ISO)

F

OT

S

O

108

DS 22

Fenvalerate

ISO

I

PY

L

O

c450

EHC 95, DS 90; HSG 34

Fipronil

N(B)

I

Pyrazole

S

O

92

Fluvalinate

N(B)

I

oil

O

282

Irritant to skin

Fluxofenim

ISO

H

oil

O

670

Formothion

ISO

I

OP

L

O

365

Fosfamid

N(U)

See dimethoate

Furconazole-cis

ISO

F

S

O

450

Guazatine

N(B)

FST

S

O

230

LD₅₀ value refers to triacetate

Haloxyfop

N(A,B)

H

S

O

393

HCH

ISO

I

OC

S

O

100

The LD₅₀ varies according to the mixture of isomers. 
The value shown has been chosen, and the technical 
product placed in Class II, as a result of the cumulative 
properties of the beta isomer

Gamma-HCH

ISO

I

OC

S

O

88

DS 12; EHC 124; HSG 54

Heptachlor

ISO

I

OC

S

O

100

DS 19; EHC 38; HSG 14

Imazalil

ISO

F

S

0

320

Imidacloprid

N(B)

I

Nitro-
guanidine

S

O

450

Iminoctadine

ISO

F

S

O

300

Eye irritant

Ioxynil

ISO

H

S

O

110

Ioxynil octanoate

(ISO)

H

S

O

390

Isoprocarb

ISO

I

C

S

O

403

Karbation

N(U)

See metam-sodium

Lindane

ISO

See gamma-HCH

MEP

N(J)

See fenitrothion

Mercaptodimethur

See methiocarb

Mercurous chloride

C

F

S

O

210

Metaldehide

ISO

M

S

O

227

Metam-sodium

(ISO)

F-S

S

O

285

Methacrifos

ISO

I

OP

L

O

678

Methasulfocarb

ISO

F

S

O

112

Methiocarb

ISO

I

C

S

O

100

Methyl isothiocyanate

ISO

F-S

S

O

72

Skin and eye irritant

Metolcarb

ISO

I

C

S

O

268

MICP

N(J)

See isoprocarb

Molinate

ISO

H

TC

L

O

720

MPMC

See xylylcarb

Nabam

ISO

F

TC

S

O

395

Goitrogenic in rats

NAC

N(J)

See carbaryl

Naled

ISO

I

OP

L

O

430

DS 39

Norbormide

ISO

R

S

O

52

2,4-PA

N(J)

See 2,4-D

PAP

N(J)

See phenthoate

Paraquat

ISO

H

P

S

O

150

Has serious delayed effects if absorbed; is relatively 
low hazard in actual use but is dangerous if 
accidentally taken orally; DS 4; EHC 39; HSG 51

Pebulate

ISO

H

TC

L

O

1,120

Permethrin

ISO

I

PY

L

O

c500

DS 51; EHC 94; HSG 33

PHC

N(J)

See propoxur

Phenthoate

ISO

I

OP

L

O

c400

DS 48

Phosalone

ISO

I

OP

L

O

120

Phosmet

ISO

I,AC

OP

S

O

230

Phoxim

ISO

I

OP

L

D

1,975

DS 31

Phthalofos

N(U)

See phosmet

Pindone

ISO

R

S

O

50

Piperophos

ISO

H

oil

O

324

Pirimicarb

ISO

AP

C

S

O

147

Polychlorcamphene

N(U)

See camphechlor

Prallethrin

ISO

I

PY

oil

O

460

Profenofos

ISO

I

OP

L

O

358

Promacyl

N(Aust)

Ix

C

L

O

1,220

Promecarb

ISO

I

C

S

O

74

Propiconazole

ISO

F

L

O

1,520

Propoxur

ISO

I

C

S

O

95

DS 25

Prosulfocarb

ISO

H

L

O

1,820

Prothiofos

ISO

I

OP

L

O

925

Prothiophos

See prothiofos

Pyraclofos

N(B)

I

OP

L

O

237

Pyrazophos

ISO

F

S

O

435

Pyrethrins

C

I

L

O

500-1,000

Mixture of compounds present in Pyrethrum,
Cineraefolium  and  other  flowers; DS 11

Pyroquilon

ISO

F

S

O

320

Quinalphos

ISO

I

OP

S

O

62

Quizalofop-p-tefuryl

ISO

H

L

O

1,012

Reglon

N(U)

See diquat

Ronnel

N(A)

See fenchlorphos

Rotenone

C

I

S

O

132-1,500

Compounds from roots of Derris and 
Lonchocarpus spp.; HSG 73

Salithion

See dioxabenzofos

SAP

N(J)

See bensulide

Sec-butylamine

See butylamine

Sevin

N(U)

See carbaryl

Sodium fluoride

ISO

I

S

O

180

Sodium hexafluorosilicate

ISO

L-S

S

O

125

Sulfallate

ISO

H

oil

0

850

Irritant to skin and eyes

Sulprofos

ISO

I

OP

oil

O

130

2,4,5-T

ISO

H

S

O

500

May contain a contaminant TCDD which affects 
toxicity: it should not exceed 0.01 mg/kg technical 
material; DS 13

TCA

ISO

The data shown refer to sodium trichloroacetic acid.

In many countries, the term TCA refers to the free acid 
(now accepted by ISO); this is a solid with an oral LD₅₀ of 400 mg/kg and if used as a pesticide is placed in 
Class II. It is highly corrosive to skin.

Terbumeton

ISO

H

T

S

O

483

Tetraconazole

ISO

F

oil

O

1,031

Thiazafluron

ISO

H

S

O

278

Thiazfluron

N(B)

See thiazafluron

Thicyofen

ISO

F

S

O

368

Thiobencarb

ISO

H

TC

L

O

1,300

Thiocyclam

ISO

I

S

O

310

Thiodan

N(U)

See endosulfan

Thiodicarb

ISO

I

S

O

66

Tolyl-methyl-carbamate

See metolcarb

Toxaphene

N(A)

See camphechlor

Tralomethrin

N(B)

I

PY

S

O

c85

Trichloroacetic acid

Tricyclazole

ISO

F

S

O

305

Tridemorph

ISO

F

oil

O

650

Vernolate

ISO

H

TC

L

O

1,780

Xylylcarb

N(B)

I

C

S

O

380